Make sure you have latest firmware , we have enabled UART HS and not HSL.
Then run the following command:
root@swi-mdm9x15: stty -F /dev/ttyHS0 -a (it will show you the status of UART whether two wire or 4 wire)
The enable 4 wire UART
root@swi-mdm9x15: stty -F /dev/ttyHS0 crtscts
then check again:
root@swi-mdm9x15: stty -F /dev/ttyHS0 -a
What you are looking for is crtscts, when it is disabled it -crtscts and when enabled it is crtscts.