Lsusb does not work on a brand-new mangOH Red from a box

root@swi-mdm9x15:~# lsusb
unable to initialize libusb: -99
root@swi-mdm9x15:~#

What can cause this problem ?

Do you have any USB devices plugged in?

When any USB device is not connected the lsusb does not work like I describe.

When I plug an FTDI / RS485 adapter it starts working

root@swi-mdm9x15:~# lsusb
Bus 001 Device 004: ID 0403:6001 Future Technology Devices International, Ltd FT232 USB-Serial (UART) IC
Bus 001 Device 003: ID 10c4:87a0 Cygnal Integrated Products, Inc.
Bus 001 Device 002: ID 0424:3503 Standard Microsystems Corp.
Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub

When I remove the adapter it is still working

root@swi-mdm9x15:~# lsusb
Bus 001 Device 003: ID 10c4:87a0 Cygnal Integrated Products, Inc.
Bus 001 Device 002: ID 0424:3503 Standard Microsystems Corp.
Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub
root@swi-mdm9x15:~#

So it is partially solved. But it is strange why it does not work after any reboot.
Theoretically, it has to detect 3 devices always

Thanks for the additional information. There was an internal issue tracking this that got closed, but I have reopened it. I will try to update this post if I hear any information.

same experience here on a mangoh green board

lsusb
unable to initialize libusb: -99